{"id":404,"date":"2025-08-22T20:31:45","date_gmt":"2025-08-22T20:31:45","guid":{"rendered":"https:\/\/mbiportfolio.com\/JamieHefley\/?p=404"},"modified":"2026-04-02T02:29:16","modified_gmt":"2026-04-02T02:29:16","slug":"blocking-wakefulness","status":"publish","type":"post","link":"https:\/\/mbiportfolio.com\/JamieHefley\/blocking-wakefulness\/","title":{"rendered":"Blocking Wakefulness"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"404\" class=\"elementor elementor-404\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c7a5b50 e-flex e-con-boxed e-con e-parent\" data-id=\"c7a5b50\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-aaf7f1d elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"aaf7f1d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1306\" height=\"1650\" src=\"https:\/\/mbiportfolio.com\/JamieHefley\/wp-content\/uploads\/2025\/09\/Editorial-Blocking-Wakefulness.png\" class=\"attachment-full size-full wp-image-203\" alt=\"\" srcset=\"https:\/\/mbiportfolio.com\/JamieHefley\/wp-content\/uploads\/2025\/09\/Editorial-Blocking-Wakefulness.png 1306w, https:\/\/mbiportfolio.com\/JamieHefley\/wp-content\/uploads\/2025\/09\/Editorial-Blocking-Wakefulness-237x300.png 237w, https:\/\/mbiportfolio.com\/JamieHefley\/wp-content\/uploads\/2025\/09\/Editorial-Blocking-Wakefulness-811x1024.png 811w, https:\/\/mbiportfolio.com\/JamieHefley\/wp-content\/uploads\/2025\/09\/Editorial-Blocking-Wakefulness-768x970.png 768w, https:\/\/mbiportfolio.com\/JamieHefley\/wp-content\/uploads\/2025\/09\/Editorial-Blocking-Wakefulness-1216x1536.png 1216w\" sizes=\"(max-width: 1306px) 100vw, 1306px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d4ad5f4 e-con-full e-flex e-con e-child\" data-id=\"d4ad5f4\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-12ad16e elementor-widget elementor-widget-heading\" data-id=\"12ad16e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Blocking Wakefulness<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a58d3dd elementor-widget elementor-widget-text-editor\" data-id=\"a58d3dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><strong>YEAR<\/strong><\/p><p>2025<\/p><p>\u00a0<\/p><p><strong>CLIENT<\/strong><\/p><p>Jennifer Fairman<\/p><p>\u00a0<\/p><p><strong>Media<\/strong><\/p><p>Photoshop<\/p><p>\u00a0<\/p><p><strong>DESCRIPTION<\/strong><\/p><p><span style=\"font-weight: 400;\">This mock editorial cover illustration for nature magazine reimagines the mechanism of Dual Orexin Receptor Antagonist (DORA) drugs, a treatment for insomnia, through a fantastical lens. DORAs work by blocking orexin, the neuropeptide that promotes wakefulness. In the scene, two knights stand guard at a gate, symbolizing the protective blockade of orexin receptors, while orexin itself takes form as a dragon, a nod to its common depiction as a serpentine chain in scientific diagrams. Behind the gate, a young girl rests peacefully, embodying the restorative sleep made possible by this defense. The piece blends science and storytelling to highlight how DORAs safeguard sleep against the forces that disrupt it.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Blocking Wakefulness YEAR 2025 \u00a0 CLIENT Jennifer Fairman \u00a0 Media Photoshop \u00a0 DESCRIPTION This mock editorial cover illustration for nature magazine reimagines the mechanism of Dual Orexin Receptor Antagonist (DORA) drugs, a treatment for insomnia, through a fantastical lens. DORAs work by blocking orexin, the neuropeptide that promotes wakefulness. In the scene, two knights stand [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1955,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[51],"tags":[],"class_list":["post-404","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-editorial"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/mbiportfolio.com\/JamieHefley\/wp-json\/wp\/v2\/posts\/404","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mbiportfolio.com\/JamieHefley\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mbiportfolio.com\/JamieHefley\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mbiportfolio.com\/JamieHefley\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mbiportfolio.com\/JamieHefley\/wp-json\/wp\/v2\/comments?post=404"}],"version-history":[{"count":13,"href":"https:\/\/mbiportfolio.com\/JamieHefley\/wp-json\/wp\/v2\/posts\/404\/revisions"}],"predecessor-version":[{"id":1676,"href":"https:\/\/mbiportfolio.com\/JamieHefley\/wp-json\/wp\/v2\/posts\/404\/revisions\/1676"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mbiportfolio.com\/JamieHefley\/wp-json\/wp\/v2\/media\/1955"}],"wp:attachment":[{"href":"https:\/\/mbiportfolio.com\/JamieHefley\/wp-json\/wp\/v2\/media?parent=404"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mbiportfolio.com\/JamieHefley\/wp-json\/wp\/v2\/categories?post=404"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mbiportfolio.com\/JamieHefley\/wp-json\/wp\/v2\/tags?post=404"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}